Quinn emanuel trial lawyers

Cheffo, Mark S.

Mark S. Cheffo



Mark S. Cheffo is Co-Chair of Quinn Emanuel’s Global Product Liability and Mass Torts Practice.  He represents defendants in products liability, insurance and mass torts litigation, serving as national coordinating and trial counsel both in large, complex matters and in individual cases. He has represented pharmaceutical and medical device manufacturers, designers of bioengineered agricultural products, and sellers of consumer and industrial products. He also has handled insurance sales practices cases and numerous toxic and environmental exposure suits.

Mr. Cheffo has been a member of several trial teams in high-profile pharmaceutical litigation, and actively manages all stages of pre-trial proceedings. He has taken and defended numerous expert and company witness depositions and has briefed and conducted numerous Daubert and Frye challenges. Mr. Cheffo has briefed and argued dispositive motions and appeals in state and federal courts throughout the country.

Mr. Cheffo secured a complete dismissal in multidistrict litigation on behalf of several pharmaceutical companies in connection with personal injury claims arising from the manufacture and distribution of generic prescription medications containing propoxyphene. He was named “Litigator of the Week” by The Am Law Litigation Daily for his role in the matter (March 8, 2012).  He successfully argued a motion to dismiss a consolidated nationwide consumer fraud class action complaint in an MDL,  and also argued the appeal in the Ninth Circuit, where the district court’s decision was affirmed. In addition, Mr. Cheffo has conducted many arbitrations and mediations dealing with a host of disputes.

Mr. Cheffo is active in local bar associations and is a frequent lecturer on products liability issues. In December 2010, he spoke at ACI’s 15th Annual Drug and Medical Device Conference (one of the largest conferences for the pharmaceutical industry) on the topic of “Negotiating and Managing Complex Settlements: Ethical and Practical Considerations.” He also is very involved in pro bono efforts. He obtained a judgment of more than $1.7 million for liability and legal fees on behalf of 11 restaurant workers in New York’s Chinatown. He also obtained a jury verdict in a defamation case and, while representing the city of New York in Bronx Supreme Court, obtained a directed verdict in a case brought by three plaintiffs who had been shot while in prison.

Mr. Cheffo was nominated for membership in the International Association of Defense Counsel. He has been selected for inclusion in Chambers USA: America’s Leading Lawyers for Business and The Best Lawyers in America.

  Representative Clients

  • Pfizer Inc.
  • Endo Pharmaceuticals Inc.
  • Amgen Inc.
  • Qualitest Pharmaceuticals
  • Intuitive Surgical, Inc.

  Notable Representations

  • National coordinating and trial counsel for a major pharmaceutical company in nationwide litigation involving several of the company’s leading prescription medications.  
  • A major biotechnology company in multidistrict litigation involving a nationwide consumer fraud action.
  • Several major pharmaceutical companies in connection with the development of risk management initiatives, labeling advice, and document retention and management.  
  • One of the world’s largest computer manufacturers in class actions challenging alleged product defects.
  • Individual and corporate property owners in connection with more than 70 cases alleging pediatric brain injuries from exposure to environmental toxins.  


  • Boston University School of Law
    (J.D., 1990)
    • Paul J. Liacos Scholar
    • American Journal of Law & Medicine:
      • Editor-in-Chief

  • State University of New York at Stony Brook
    (B.A., with Honors, 1987)
    • Pi Sigma Alpha National Political Science Honor Society
    • Phi Alpha Theta International History Honor Society


The State Bar of New York; United States Court of Appeals: First Circuit, Second Circuit, Fourth Circuit, Sixth Circuit, Ninth Circuit; United States District Courts: Eastern District of New York, Southern District of New York

  Prior Associations

  • Skadden, Arps, Slate, Meagher & Flom LLP:
    • Partner, 1994-2013

  • Strook & Strook & Lavan LLP:
    • 1990-1994


  • Named Law360 Product Liability MVP, 2017 
  • Named “Litigator of the Week” by The Am Law Litigation Daily, 2012.

Professional Activities

  • New York City Bar Association
  • International Association of Defense Counsel